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In addition, a high proportion (>2/3) of patientswith NAION have sleep apnea, which may partlyexplain why approximately three-fourths of patientswith NAION discover visual loss on first awakening orwhen they first use vision critically after sleeping (Mojonet al., 2002).
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We used to walk with one another andtalk about what God is doing in our lives . Collagen type IV is also the target in autoimmunediseases such as Goodpasture syndrome and Alport'sposttransplantation disease. Imaging studies of theneck and shoulder may be indicated, and serum studies toassess for a broader autoimmune process may be needed.The differential diagnosis includes stroke, acute radicu-lopathy, and traumatic injury to the shoulder or plexus,such as shoulder dislocation or rotator cuff injury. [ 133] reported successful up-scaling of rAAVproduction using the BEV system up to 200 L with a single-use stirred-tank bioreac-tor with a paddle-drive agitator [ 133].
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As Figure 1.7shows, comparisons of the LD doses of toxicants A, B, andC indicate the potency (toxicity relative to the dose used) ofeach chemical.